1.) There will be bots on day one of release. Many, many different kinds. Not just simple autohotkey ones. You are greatly underestimating the community. Again, this is 2011 and not 2001. Duping will be impossible in D3 (it can't be eliminated in D2), but Blizzard can never stop botting.
2.) Again, what makes you think you can outfarm hundreds of thousands of Chinese farmers to get these items? You never had to compete against massive farming operations in Diablo 2. You have no idea what you're talking about.
3.) I'm sure your mastery of manipulating the chat gem will make your drops better than the drops of millions of other people around the globe...
4.) Sharding loot doesn't affect the supply of useful items at all. It certainly will make "enchanting mats" worthless though.
5.) You're underestimating the bot community and the farming industry. If there was a considerable profit potential on WoW hard mode bosses the farmers would run them in a second. Only some guilds sell BoP loot slots in raids to slugs because it's annoying and it's just easier to have them farm ores and other mats.
Don't quit your day jobs is all I'm trying to say here. You can't compete with the farming industry.
You make a lot of unreasonable assumptions, particularly bots on release. You also don't seem to understand the game too well. I'm not going to waste my time arguing with you. I've made my points and stick by them.