Q u o t e: Yes, I just read rune saturation, but there is really no reason not to apply this to items in general.
In d2, there was a GREAT feature to take items out of the economy...that was having your character deleted after 6 or so months of no use. That..and the ladder.
Both of which are not going to be in d3. So...how are we going to get rid of items? You might say crafting...but if crafting yields the strongest item, then that item will eventually get oversaturated. What then? How do you get rid of that item?
There will need to be a way to take items out of the game permanently, without creating another item in the process.
What are they going to do?
Back to the OP... I think you haven't thought about all the facts:
-Many top end items will probably be ethereal or something alike.
-After I saw there is going to be REAL CASH AH (lol!) everything became possible, there may be some items that could last for a set time after you loot time, you know, like "lasts 7 days after equiping".
-I once played a Diablo 2 mod where you had to transmute uniques with a reagent that gave back arcane shards, and those shards transmuted into arcane crystals, etc... whatever, the point is that you might need one of the best unique legendary items to be sent to the jeweller artisan to extract power so you can get access to a type of rune that you can't craft nor loot (remember for example that you can't craft runes further than Thul), or a jewel that will have different stats depending on the grade of "perfect" that the item is (remember Iron Golem).
-You might have a lower chance to get that high end item than the chance you have to get a Zod in D2 at the moment.
-I don't know wether we have a horadric cube-ish feature in D3, which brought a LOT of items to D2, however I'm certain that there won't be BOTS, that used to loot everything by people who left the game to sleep and when they come back 30 hours after they have 4 SoJs for free that they sell out with no effort.
-Magic find feature has been totally revamped afaik, and now it doesn't matter wether it's a solo rush or a full house farming party, only your MF will affect yourself, and the items you can pick up can't be seen by any other player. Hopefully, there aren't going to be as many MF only character builds, there will be some though, you can't stop grinder from sucking and thrying to find 12908312 times better gear to try to stand a chance.
-No town portals, this may look like "What the $%$% are you talking about? Off topic?" but it makes sense,, if you can't go back to the city when your inventory is full you will have to decide what you pick and what not.
After I thought about all this, I came to the conclussion that items won't be flooding around so much.
Q u o t e: Acting is easy, thinking is hard, and to put one's thoughts into action is the most difficult thing in the world.